MORAD-RNA/MORAD-RIDE
Reinforcement Learning • Updated
AI & ML interests
RNA inverse design, reinforcement learning, diffusion models
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MORAD
Reinforcement Learning with Multi-Objective Rewards for RNA Inverse Design
MORAD post-trains a single backbone-conditioned RNA diffusion policy online with a six-objective reward covering tertiary geometry, base pairing, ensemble behavior and sequence composition. The trained policy designs sequences for a new target backbone directly, with no per-target optimization.
- 🧬 MORAD-RIDE: the released model, post-trained from pretrained RIDE
- 📦 MORAD-Targets: 527 training and 153 test RNA backbone targets
- 💻 Code: training, evaluation and reproduction scripts
- 🌐 Project page: overview, method and results